Saturday, December 29, 2012

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Friday, December 28, 2012

December 28: Favorite Sites Friday | InTheCapital

December 28: Favorite Sites Friday

Today at 1:00 pm by Kiana

Reported by foodem.com, the online wholesale food marketplace-

Happy holidays! This is our last Favorite Sites Friday of 2012. Check out the list below.

  1. Foodservice Director: As the online companion to Foodservice Director Magazine, FoodserviceDirector.com is a resource for non-commercial foodservice operators to learn about innovations and innovators through trends, news and insights. The site now has new features which include new online-only content such as Recipe Revamp, where we talk to chefs about how they make popular recipes healthier, and Snapshots, where operators can find inspiration through photos. Existing features include the Editors? blog, where readers can read commentary from FSD?s editors on trends, challenges facing operators and, occasionally, the quirkier side of the industry, and Five Questions, where we gather quick takes from industry leaders on hot topics.
  2. Restaurant Hospitality: RH is designed to keep its readers informed of industry trends and happenings, and helps them run their operations more profitably. It?s dedicated to the success of full-service restaurants and edited for chefs and other commercial foodservice professionals on a monthly basis, including those operating full-service restaurants, hotels, resorts, clubs, catering operations, and other commercial foodservice operations. Restaurant Hospitality regularly includes topics such as, new food and equipment products and trends, menu and recipe ideas, industry news, new technology, food safety, emerging new concepts, consumer attitudes and trends, labor and training, and profiles of successful operations.
  3. Restaurant News: RestaurantNews.com offers an affordable, dependable, effective outlet for your restaurant news. Independent operators, as well as, national chains, PR companies and other restaurant related businesses have turned to RestaurantNews.com to distribute their restaurant news and help build their brands since 1999.
  4. Locallectual: Creators Karen and Jessica call Locallectual ?the ultimate thoughtful consumer? database. Site visitors can search Locallectual to find products, as well as food grown close to your neighborhood. The site can be used to identify locally-owned and operated retailers in your neighborhood, ones that also support local and domestic producers, and locally-owned and operated eateries that partner with local farms.
  5. Food Arts: Food Arts serves the informational needs of the entire full-service segment of the restaurant/hotel industry. Exposing the latest and hottest restaurant openings, business-building tips from colleagues, menu and food innovations, how-to culinary demos, tabletop fashions, state-of-the-art equipment, marketing ideas, and recipes galore, Food Arts is known for keeping its readers on the cutting edge with authoritative coverage of trends, news, and inspiration from across the globe.

Be sure to share your food-related site with us, we?d love to feature it in our next Favorite Sites Friday post. Leave us your URL in the comments area or shoot us a tweet @foodem.

Source: http://inthecapital.com/channels/december-28-favorite-sites-friday/

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Critics: Myriad blocks cancer answers by impeding data sharing ...

Patents ? Utah company says it has aided, not hindered, research, care.

Tory Galloway thought her negative result on a widely-used test sold by Utah-based Myriad Genetics Inc. cleared her DNA as a cause for her fallopian tube cancer.

She happily advised her four sisters that the disease didn?t result from a family trait. The relief from the December 2010 test, though, was short lived. In October, after getting results from a broader scan at the University of Washington that included dozens of genes, she learned the truth: Her cancer was caused by a mutation that wasn?t included in the Myriad product.

"It makes me nuts to even think about it," said Galloway, a landscape designer in Indianola, Wash.

The broader test, created by University of Washington researchers, uses technology to identify as many cancer risks as possible. There?s one problem: Such a test can?t include the BRCA1 and BRCA2 genes that are the most common inherited causes for breast and ovarian cancer because Myriad owns the patents on them. This prevents other U.S. laboratories from using them in a commercial test.

In the mid-1990s, Myriad helped kick-start the gene-testing revolution by pinpointing the two BRCA genes. Now, the world?s biggest genetic testing company for breast cancer, with a market value of $2.2 billion, is under attack by researchers, genetic counselors, doctors, and their patients.

Besides stifling competitors from offering combination tests, including the BRCA genes, critics also said the company won?t share data from decades of testing that could aid research into how best to interpret screening. They said Myriad doesn?t adequately respond when other researchers find added BRCA mutations that address risks their current tests don?t cover.

"What is at stake is the way we want our health-care system to work," said Robert Cook-Deegan, a professor of public policy, biology, and medicine at Duke University in Durham, North Carolina, who supports limits on gene patents. "The testing has been set up by Myriad to optimize this business model. It is not set up to optimize public health outcomes."

The dispute, which has grown in intensity as more and more cancer-causing mutations are found, has spilled out of the laboratories and clinics into the U.S. Supreme Court. A ruling next year in a case challenging Myriad?s hold on the BRCA patents could either support the company?s profit-driven motives or redefine a nascent industry in a way that affects millions of dollars in revenue.

Myriad officials reject the criticisms, saying they offer faster, more accurate testing for harmful mutations in breast cancer genes than any other laboratory in the world, and that its patents haven?t hindered research or patient care.

"Myriad has never done anything to harm patients," CEO Peter Meldrum said during an interview at his company?s headquarters in Salt Lake City. "We have the most accurate results, we give the fastest results." There has never been a reported case in which Myriad wrongly told that a woman she had a cancer-causing mutation, he said.

story continues below

Carol Mackoff, 70, a Chicago-based managing director for Rice Financial Products Co., says Myriad "saved my life."

Mackoff tested positive on a Myriad test for a BRCA1 mutation in 2002 after visiting an ovarian cancer prevention program at Northwestern Memorial Hospital in Chicago, she said in a telephone interview. Within weeks, she had her ovaries removed to prevent ovarian cancer, and later in 2009 had a prophylactic double mastectomy.

Without the Myriad test, "I would have had cancer," she said. "The fact that they developed these tests and gave me a tool to work with to allow me to prevent getting cancer, I owe them everything."

Faster, cheaper DNA testing is revolutionizing medical care. Nowhere has the impact been felt more strongly than in breast cancer. A woman who tests positive using Myriad?s tests carries as much as an 80 percent chance that she will get breast cancer in her lifetime. Testing helps women take charge of their medical future, providing options that can include preventative surgery and more extensive monitoring.

Widespread use of the tests has made Myriad an unabashed financial success. The company?s testing business, led by its flagship $3,340 BRCA product, carries an 87 percent gross profit margin that in fiscal 2012 generated $496 million in sales, according to Myriad.

That?s helped boost the company?s shares 30 percent this year.

Next Page >

Copyright 2012 The Salt Lake Tribune. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

Source: http://www.sltrib.com/sltrib/money/55537762-79/myriad-cancer-test-brca.html.csp

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Obama back from Hawaii, Congress bickers on cliff

President Barack Obama waves to reporters as he steps off the Marine One helicopter and walks on the South Lawn at the White House in Washington, Thursday, Dec. 27, 2012, as he returns early from his Hawaii vacation for meetings on the fiscal cliff. (AP Photo/Charles Dharapak)

President Barack Obama waves to reporters as he steps off the Marine One helicopter and walks on the South Lawn at the White House in Washington, Thursday, Dec. 27, 2012, as he returns early from his Hawaii vacation for meetings on the fiscal cliff. (AP Photo/Charles Dharapak)

President Barack Obama walks past a Marine honor guard as he steps off the Marine One helicopter and walks on the South Lawn at the White House in Washington, Thursday, Dec. 27, 2012, as he returned early from his Hawaii vacation for meetings on the fiscal cliff. (AP Photo/Charles Dharapak)

House Minority Whip Rep. Steny Hoyer of Md. gestures during a news conference in Washington, Capitol Hill, Thursday, Dec. 27, 2012, where he urged House Republicans to end the pro forma session and call the House back into legislative session to negotiate a solution to the fiscal cliff. (AP Photo/ Evan Vucci)

(AP) ? President Barack Obama returned to the White House on Thursday from a vacation shortened by government gridlock while Democrats and Republicans snarled across a partisan divide and showed no sign of compromise to avoid year-end tax increases and spending cuts.

Adding to the woes confronting the middle class was a pending spike of $2-per-gallon or more in milk prices if lawmakers failed to pass farm legislation by year's end.

White House aides disputed reports that Obama was sending lawmakers a scaled-down plan to avoid the "fiscal cliff" of tax increases and spending cuts. They gave no indication he would invite congressional leaders to a White House meeting either late Thursday or possibly on Friday.

Top Senate leaders said they remain ready to seek a last-minute agreement. But a little more than four days from the deadline, there was no legislation pending in either the House or the Senate to prevent the tax hikes and spending cuts that economists say could send the economy into a recession.

Far from conciliatory, the rhetoric was confrontational and at times unusually personal.

Senate Majority Leader Harry Reid, D-Nev., accused House Speaker John Boehner of running a dictatorship, citing his refusal to call a vote on legislation to keep taxes steady for most while letting them rise at upper incomes. The bill "would pass overwhelmingly," Reid predicted, and said the Ohio Republican won't change his mind because he fears it might cost him re-election as speaker when the new Congress convenes next week.

Boehner seems "to care more about keeping his speakership than keeping the nation on a firm financial footing," he said in remarks on the Senate floor.

A few hours later, Senate Republican leader Mitch McConnell expressed frustration and blamed the standoff on Obama and the Democrats. "Republicans have bent over backwards. We stepped way, way out of our comfort zone," he said, referring to GOP offers to accept higher tax rates on some taxpayers.

"We wanted an agreement, but we had no takers. The phone never rang and so here we are five days from the new year and we might finally start talking," McConnell said.

Still, he warned: "Republicans aren't about to write a blank check for anything the Democrats put forward just because we find ourselves at the edge of the cliff."

Brendan Buck, a spokesman for Boehner, responded in a similar vein to Reid's comments. "Harry Reid should talk less and legislate more if he wants to avert the fiscal cliff. The House has already passed legislation to do so," he said, referring to a measure that extends existing cuts at all income levels.

Addressing the GOP rank and file by conference call, Boehner said the next move is up to the Senate, which has yet to act on House-passed bills to retain expiring tax cuts at all income levels and replace across-the-board spending cuts with targeted savings aimed largely at social programs.

"The House will take this action on whatever the Senate can pass - but the Senate must act," he said, according to a participant in the call.

At the same time, Boehner told Republican lawmakers the House would convene on Sunday evening.

The risk of higher milk prices stems from the possibility that existing farm programs will expire at year's end, and neither chamber of Congress has scheduled a vote on even a temporary extension to prevent a spike. There have been unverified estimates that the cost to consumers of a gallon of milk could double without action by Congress.

The president flew home from Hawaii overnight after speaking with top congressional leaders.

Before leaving the White House last Friday, the president had called on lawmakers to pass scaled-down legislation that prevents tax increases for the middle class, raises rates at upper incomes and renews expiring unemployment benefits for the long-term jobless. He said he still supports a more sweeping measure to include spending cuts to reduce deficits, but said they could wait until the new year.

That capped an unpredictable week in which Boehner pivoted away from comprehensive deficit reduction talks with Obama to an aborted attempt to push legislation through the House that retained existing tax levels except above $1 million. Anti-tax Republicans rebelled at raising rates on million-dollar earners, and Boehner backpedaled and canceled the planned vote.

Without congressional action, current tax rates will expire on Dec. 31, resulting in a $536 billion tax increase over a decade that would touch nearly all Americans. In addition, the military and other federal departments would have to begin absorbing about $110 billion in spending cuts.

Failure to avoid the "fiscal cliff" doesn't necessarily mean tax increases and spending cuts would become permanent, since the new Congress could pass legislation cancelling them retroactively after it begins its work next year.

But gridlock through the end of the year would mark a sour beginning to a two-year extension of divided government that resulted from last month's elections in which Obama won a new term and Republicans retained their majority in the House.

The tax issue in particular has been Obama's first test of muscle after his re-election in November. He ran for a new term calling for higher taxes on the wealthy, and postelection public opinion polls show continued support for his position.

Boehner's decision to support higher rates on million-dollar earners marked a significant break with long-standing GOP orthodoxy, but the resistance among his rank and file so far has trumped him as well as any mandate the president claims.

___

Associated Press writers Alan Fram and Jim Kuhnhenn contributed to this report.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2012-12-27-Fiscal%20Cliff/id-f2a2a0d433c84fd9a5ac35d15d1246c9

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'Yak insurance' plan saving Nepal's endangered snow leopard | The ...

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New purported BlackBerry Z10 specs emerge: 1.5GHz processor, 2GB RAM, 8MP camera

In a rare and now controversial investigation, scientists have been asked by Connecticut's medical examiner?to study Sandy Hook shooter Adam Lanza's DNA?? but the DNA community doesn't think that's such a good idea. Though details on the research are scant, University of Connecticut geneticists will apparently be looking for?biological clues that might explain Lanza's extreme violent behavior.?The New York Times's Gina Kolata reports that this undertaking is thought to be the first time scientists have studied the genome of a mass killer. ...

Source: http://news.yahoo.com/purported-blackberry-z10-specs-emerge-1-5ghz-processor-160048161.html

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Brain scan can sort dementia by type

Scientists say they have found a way to distinguish between different types of dementia without the need for invasive tests, like a lumbar puncture.

US experts could accurately identify Alzheimer's disease and another type of dementia from structural brain patterns on medical scans, Neurology reports.

Currently, doctors can struggle to diagnose dementia, meaning the most appropriate treatment may be delayed.

More invasive tests can help, but are unpleasant for the patient.

Continue reading the main story

?Start Quote

This could be used as a screening method and any borderline cases could follow up with the lumbar puncture or PET scan?

End Quote Lead researcher Dr Corey McMillan Distinguishing features

Despite being two distinct diseases, Alzheimer's and frontotemporal dementia, share similar clinical features and symptoms and can be hard to tell apart without medical tests.

Both cause the person to be confused and forgetful and can affect their personality, emotions and behaviour.

Alzheimer's tends to attack the cerebral cortex - the layer of grey matter covering the brain - where as frontotemporal dementia, as the name suggests, tends to affect the temporal and frontal lobes of the brain, which can show up on brain scans, but these are not always diagnostic.

A lumbar puncture - a needle in the spine - may also be used to check protein levels in the brain, which tend to be higher in Alzheimer's than with frontotemporal dementia.

A team at the University of Pennsylvania set out to see if they could ultimately dispense of the lumbar puncture test altogether and instead predict brain protein levels using MRI brain scans alone.

They recruited 185 patients who had already been diagnosed with either Alzheimer's disease or frontotemporal dementia and had undergone a lumbar puncture test and MRI scanning.

Continue reading the main story

Dementia

  • There are many causes of dementia, with Alzheimer's the most common
  • More than half a million people in the UK have Alzheimer's disease
  • Frontotemporal dementia tends to affects people who are younger - under 65 - and can affect a personality and behaviour
  • Other types of dementia include vascular dementia and dementia with Lewy bodies

The researchers scrutinised the brain scans to see if they could find any patterns that tallied with the protein level results from the lumbar puncture tests.

They found the density of gray matter on the MRI scans correlated with the protein results.

The MRI prediction method was 75% accurate at identifying the correct diagnosis.

Although this figure is some way off an ideal 100%, it could still be a useful screening tool, say the researchers.

Lead researcher Dr Corey McMillan said: "This could be used as a screening method and any borderline cases could follow up with the lumbar puncture or PET scan."

Dr Simon Ridley, Head of Research at Alzheimer's Research UK, said: "This small study suggests a potential new method for researchers to distinguish between two different types of dementia, and a next step will be to investigate its accuracy in much larger studies involving people without dementia.

"While this method is not currently intended for use in the doctor's surgery, it may prove to be a useful tool for scientists developing new treatments. The ability to accurately detect a disease is vital for recruiting the right people to clinical trials and for measuring how well a drug may be working.

"Ultimately, different causes of dementia will need different treatment approaches, so the ability to accurately distinguish these diseases from one another will be crucial."

The only drug currently licensed in England and Wales for treating frontotemporal dementia is rivastigmine.

There are four licensed treatments for Alzheimer's - donepezil, galantamine, rivastigmine and memantine.

Source: http://www.bbc.co.uk/news/health-20836083#sa-ns_mchannel=rss&ns_source=PublicRSS20-sa

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