Saturday, December 1, 2012

Cheap Storage, Garage | Home Improvement Genuis

Cheap Storage, Garage

Cheap Storage Ideas

For most people, a garage happens to be a really cluttered dumping ground where you may choose to put practically anything and everything which you no longer want in your house. In general, it becomes really difficult to find things as and when you require them. Your garage will also become really messy. Using some really cheap ideas, you will be able to make your garage look quite tidy. You may even be able to make room for a car.

Conduct a Garage Sale

Holding a garage sale happens to be one of the best ways to increase storage space. Get rid of all unwanted items for a weekend sale in your front yard. Get the neighbors involved in order to turn it into a really big event. It will make it really easy for you to organize the rest of the items. Some extra money can be made in the process.

Create Item Zones

You need to group like items into item zones. For instance, one area of the garage may be used solely for sporting goods. Another area may be used for automotive supplies and a third area may be used for gardening tools. You must keep the gardening items near a side door or the garage opening which allows easy access during really warm months.

Install Shelves

You are well advised to purchase inexpensive shelves for the garage walls or you need to make your own. You have to place smaller items in cardboard boxes and keep it on the shelves. Get them labeled so as to identify the contents. The lesser items you have on the floor, the more room you will have for bigger things

Make Use of the Ceiling

Cheap Storage, Garage

Cheap Storage Ideas

You need to use garage?s ceiling in an attempt to create additional floor space. You may use inexpensive hooks in order to hang items like bicycles, ropes, step ladders and cords safely during the winter months

Mobilize the Trash

If trash cans are kept in the garage, use those which have wheels it will be easier for you to create more storage space. If you store cans along the garage wall, you need to place additional shelving above the cans to use that space.

This discussion on cheap storage spaces ends here.

Source: http://homeimprovementgenuis.com/familiarize-yourself-with-ideas-for-cheap-storage/?utm_source=rss&utm_medium=rss&utm_campaign=familiarize-yourself-with-ideas-for-cheap-storage

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Source: http://capaciousness-wallenstein.blogspot.com/2012/11/cheap-storage-garage-home-improvement.html

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Online marketing Strategies

Why is any web business a runaway success? A great launch is good and simple but in the end it does not take meticulous planning and implementation of website marketing strategies which makes the online business a revenue generator. A mix of good online marketing strategies like online marketing or Ezine publishing or blogging, requires research and organizing.

Internet comes complete with affiliate marketing software as well as other marketing techniques like quick Ezine publishing, to produce your online business a million-dollar industry with just a couple of hours and days spent about that. Well, without a doubt that overnight success of online marketing strategies is often a carefully publicized myth.

Successful Internet Marketing Strategies are not devised in one day or two, but take effort, meticulous research, implementation and monitoring of assorted marketing methods like Ezine publishing, Online marketing, banner advertising, SEO (Search Engine Optimization), blogs, Good adsense, etc.

Create a direct impact along with your online marketing strategy by implementing a mixture of these proven marketing strategies.

Targeted Web marketing: Choose the consumer to your web business. Survey the consumer categories and usefulness of your respective product for this. Organize your Web marketing strategy around your niche customers. Niche internet marketing techniques requires optimal by using other affiliate marketing methods to be successful.

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Korean fried chicken wings

These?double-fried chicken wings render out the fat and results in an ultra crispy skin. A delicious ginger soy glaze and a sprinkling of sesame seeds are perfect finishing touches.

By Hong Pham and Kim Dao,?The Ravenous Couple / November 30, 2012

Korean fried chicken wings coated with super-fine Wondra flour and deep fried twice to make a crispy skin. A ginger goy glaze and toasted sesame seeds complete the delicious flavor of these wings.

The Ravenous Couple

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Southern California is a huge ethnic melting pot/salad bowl with large ethnic groups such as Vietnamese, Koreans, Chinese, Thai, Philipinos, and Latinos ? and each group has made it?s mark on the culinary landscape. One such culinary notch is Korean fried chicken wings.

Skip to next paragraph Hong and Kim Pham

Ravenous Couple

A couple that cooks together stays together, says Hong and Kim Pham. They love to cook and believe good food not only brings people together, but also strengthens bonds and forges wonderful memories. Hong and Kim specialize in Asian, specifically Vietnamese cuisine, and love to share not only our food but also their culture.

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While fried chicken may be something American?s consider their own, the Korean style is also extremely delicious. Their method of a very lightly battered and double fried chicken wing renders out the fat and results in an ultra crispy and delicious wing. Add to that a variety of glazes such as ginger soy and spicy glaze, it?s no wonder Korean fried chicken joints are popping up all over the West and East Coasts.

We don?t deep fry very often but we had access to a deep fryer and had to make our version of Korean fried chicken wings for a birthday party. We adapted?Maangchi?s Sweet and Crispy Fried Chicken to make it similar to the ones we?ve had here in Los Angeles. The Korean chicken wings at Kyochan or Bon Chan have a very thin crust and so instead of using your typical flour and egg batter, we used Wondra flour which is a super fine flour ? great for crispying things up ? a tip we got from Chef Eric Ripert on his cooking show, Avec Eric.

Korean Fried Chicken Wings with Ginger Soy Glaze

? (adapted from Cooking Korean Food with Maangchi)

2-3 lbs. chicken wings (tips discarded, and wings cut at the joints-washed and pat dry)

1 cup of Wondra flour

1 teaspoon salt

1 teaspoon pepper

Soy Ginger Glaze:

?1 cup water

1 cup thinly sliced ginger

3 tablespoons soy sauce

1/2 cup brown sugar

1/4 cup vinegar

2 tablespoon honey or corn syrup

1-2 tablespoons Korean fermented chile or rooster brand garlic chile or red pepper flakes (adjust according to your tastes)

1/4 cup toasted sesame seeds (optional)

First prep the chicken wings, wash, and pat dry with paper towel. In a mixing bowl, combine about 1 cup of Wondra flour, salt, and pepper. Dredge the chicken wings in the flour mixture to get a fine light coat.

Heat some cooking oil in a deep fryer or a deep frying pan to about 350 degrees F. Fry chicken wings, in batches if necessary, about 5 minutes. Remove, and shake any excess flour/grit off and allow to cool.

Now in a small saucepan, add the water, ginger, soy sauce, vinegar, chile, sugar and bring to boil. Then add the honey/corn syrup and reduce by half and it will be a thick maple syrup like consistency and set aside.

Re-fry the wings until crispy golden brown, about another 5-8 minutes. Drain on frying rack or paper towels. Dredge or brush on the soy ginger glaze. We also like to finish with some toasted sesame on top.

The Christian Science Monitor has assembled a diverse group of food bloggers. Our guest bloggers are not employed or directed by The Monitor and the views expressed are the bloggers' own and they are responsible for the content of their blogs and their recipes. All readers are free to make ingredient substitutions to satisfy their dietary preferences, including not using wine (or substituting cooking wine) when a recipe calls for it. To contact us about a blogger, click here.

Source: http://rss.csmonitor.com/~r/feeds/csm/~3/51LgEMKORGU/Korean-fried-chicken-wings

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X-rays expose blueprint for possible sleeping sickness drug

Friday, November 30, 2012

Using the world's most powerful X-ray laser, scientists have exposed a possible Achilles' heel of the sleeping sickness parasite that threatens more than 60 million people in sub-Saharan Africa. The sophisticated analysis revealed the blueprint for a molecular plug that can selectively block a vital enzyme of the parasite Trypanosoma brucei. Plugging such a tailor-made molecule into the right place of the enzyme would render it inactive, thereby killing the parasite. The team led by DESY scientist Prof. Henry Chapman from the Center of Free-Electron Laser Science (CFEL), Prof. Christian Betzel from the University of Hamburg and Dr. Lars Redecke from the joint Junior Research Group "Structural Infection Biology using new Radiation Sources (SIAS)" of the Universities of Hamburg and L?beck report their findings in the journal Science. "This is the first new biological structure solved with a free-electron laser," said Chapman.

The researchers had investigated tiny crystals of the parasite's enzyme cathepsin B with intense X-rays from the free-electron laser Linac Coherent Light Source (LCLS) at the US National Accelerator Laboratory SLAC in California. "The enzyme had emerged as a promising drug target in earlier trials", said Redecke, one of the first authors of the scientific paper. "The knockdown of this essential enzyme in the parasite did cure the infection in mice."

But the same enzyme is also part of the human - and in fact of all mammalian - biochemistry, and blocking it has severe consequences. With their analysis the scientists could now pinpoint distinctive structural differences between the human and the parasite's form of the enzyme. "This should in principle allow for designing a molecule that selectively blocks the parasite's enzyme while leaving the patient's intact", explained the other first author of the paper, Karol Nass, PhD student at the Hamburg School for Structure and Dynamics in Infection (SDI), funded by the Excellence Initiative of the German Federal State of Hamburg (LEXI), The researchers stress that while the finding raises hopes, a possible new drug is still a long way to go.

Sleeping sickness, or human African trypanosomiasis (HAT), is transmitted by the bite of the tsetse fly. The Trypanosoma parasites invade the central nervous system, and without treatment the infection is usually fatal. The disease occurs in 36 sub-Saharan countries and affects mostly poor populations living in remote rural areas. Thanks to intensified control measures the number of reported cases fell steeply in recent years, but there are still millions at risk. Current treatments of HAT rely on anti-parasitic drugs developed without knowledge of the biochemical pathways. They are not always as effective and as safe as desired, and the parasites are increasingly becoming resistant to these drugs. New drugs that selectively kill the parasite without affecting the patient's own organism would be of great use.

With cathepsin B the scientists applied a novel approach by investigating tiny crystals of the enzyme that were grown in insect cells in vivo. This way the enzyme was frozen in its natural configuration that includes a native inhibitor. Because cathepsin B works as a sort of molecular scissors cutting away at other proteins, it is produced by the cell in an inhibited form and only activated when needed. In the inhibited form a small peptide molecule is blocking the cutting edge of the molecular scissors. "With the peptide still in place we could peer below a previously impenetrable part of the cathepsin B structure ", explained Betzel. There, the analysis revealed significant differences between the peptide binding sites at the parasite's and the human form of cathepsin B. "This way, nature provided us with a blueprint of what an artificial inhibitor for the parasite's enzyme could look like." The next step would be to synthesise such a tailor-made plug and test it in the lab.

The molecular structure of the enzyme was solved to the atomic level by shooting bright X-ray flashes at the tiny cathepsin B crystals, which were only about a micron (a thousandth of a millimetre) in diameter and about ten microns long on average. Crystals scatter X-rays in a characteristic way that depends on their inner structure. From the resulting diffraction pattern the structure of the crystals can be calculated, in this case revealing the structure of the enzyme. Today, crystallography is a standard technique to analyse biomolecules. Usually, scientists use modified bacteria to produce biomolecules in large amounts and try to crystallise them into the largest possible sizes of high-quality crystals afterwards. The in vivo crystallisation pioneered at the labs of Betzel and Prof. Michael Duszenko at the University of T?bingen, who is also a member of the research team, employs living cells to produce crystals. In contrast to standard crystallisation experiments, only in vivo crystallisation yielded suitable crystals of cathepsin B in a natively inhibited form.

But the in vivo crystals are still so small that only X-ray lasers like LCLS are bright enough to produce sufficiently detailed diffraction images. The LCLS belongs to a novel class of scientific light sources called free-electron lasers that are based on powerful particle accelerators. In these machines, electrons are accelerated to high speeds, or energies, and are then forced on a tight slalom course. In every bend each electron emits a tiny flash, and all the flashes add up to an incredibly strong X-ray pulse with laser properties, that allows to resolve structures like the natively inhibited cathepsin B molecule.

To solve the cathepsin B structure the researchers had to record hundreds of thousands of diffraction images that were painstakingly stitched together afterwards. As each crystal is destroyed when hit by the powerful X-ray flash, the team fed a stream of crystals in a watery solution through a thin nozzle into the laser path. The X-ray laser fired away at 120 shots per second, where on average only every eleventh shot actually hit a crystal. This resulted in a total of 293,195 diffraction images recorded. These could only be processed with massive parallel computing, to first generate a three-dimensional map of the entire diffracting signals of the enzyme from which an image of its structure was calculated. The final result revealed the enzyme's structure with a resolution of 2.1 ?ngstr?m (one ?ngstr?m is a tenth of a nanometre or a ten-millionth of a millimetre). "Interestingly, this discovery comes exactly at the centenary of the publication of the famous X-ray diffraction equation by William Bragg in 1912," Chapman pointed out.

The team included members from DESY, the Universities of Hamburg, L?beck, T?bingen, Uppsala and Gothenburg, the Arizona State University, SLAC, Lawrence Livermore National Laboratory, the Max Planck institute for medical research in Heidelberg and the Max Planck advanced study group at CFEL. CFEL is a joint venture of DESY, the Max Planck society and the University of Hamburg. DESY is the leading German accelerator centre and one of the leading worldwide.

###

Helmholtz Association of German Research Centres: http://www.helmholtz.de/en/index.html

Thanks to Helmholtz Association of German Research Centres for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/125614/X_rays_expose_blueprint_for_possible_sleeping_sickness_drug

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The US Is Building Secret Site 911 In Israel - Business Insider

Leave it to legendary Walter Pincus from the Washington Post?to flesh out a Request for Proposal construction project planned for Israel called Site 911.

The oddly named project will cost up to $100 million, take more than two years to complete, and can only be built by workers from specific countries with proper security clearances. Palestinians need not apply.

When complete the well-guarded compound will have five levels buried underground and six additional outbuildings on the above grounds, within the perimeter. At about 127,000 square feet, the first three floors will house classrooms, an auditorium, and a laboratory ? all wedged behind shock resistant doors ? with radiation protection and massive security.

Only one gate will allow workers entrance and exit during the project and that will be guarded by only Israelis.

The bottom two floors are smaller, according to the full line of schematics uploaded to the Army's Acquisition Business Web Site, and possibly used for equipment and storage.

As impressive as the American design features already are,?Ada Karmi-Melamede Architects will decorate the entire site with rocks it chooses, but are paid for by the contractor, and provide three outdoor picnic tables.

Pincus also found this detailed description of the mezuzahs that will adorn every door in the facility:

These mezuzas, notes the [US Army] Corps, ?shall be written in inerasable ink, on .?.?. uncoated leather parchment? and be handwritten by a scribe ?holding a written authorization according to Jewish law.? The writing may be ?Ashkenazik or Sepharadik? but ?not a mixture? and ?must be uniform.?

Also, ?The Mezuzahs shall be proof-read by a computer at an authorized institution for Mezuzah inspection, as well as manually proof-read for the form of the letters by a proof-reader authorized by the Chief Rabbinate.? The mezuza shall be supplied with an aluminum housing with holes so it can be connected to the door frame or opening. Finally, ?All Mezuzahs for the facility shall be affixed by the Base?s Rabbi or his appointed representative and not by the contractor staff.?

Along with this request is another called 911 Phase 2.

Also in the $100 million range, Pincus finds the??complex facility with site development challenges? requiring services that include ?electrical, communication, mechanical/?HVAC [heating, ventilation, air conditioning] and plumbing? requirements telling; and along with the fact that the contractor must posses a U.S. or Israeli Secret Security Clearance, he believes this phase to be a secure command center.

Pulitzer Prize winning, Yale grad, born in 1932 whose worked intelligence and media in D.C. since 1955 closes his piece with these shadowy words.

"The purpose of Site 911 is [un] clear."

Source: http://www.businessinsider.com/the-us-is-building-secret-site-911-in-israel-2012-11

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Holy Crap, Someone Made a Real-Life Pixar Desk Lamp

Great news for anyone who's ever dreamed of their boring desk lamp coming to life as their lovable sidekick. Inspired by the animated Luxo lamp that greets moviegoers at the start of every Pixar film, Adam Ben-Dror, Shanshan Zhou, and Joss Doggett created the Pinokio lamp which moves and reacts to its environment with what appears to be genuine emotions. More »


Source: http://feeds.gawker.com/~r/gizmodo/full/~3/NuQV1ZWgh4U/holy-crap-someone-made-a-real+life-pixar-desk-lamp

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